Indians Taking Dolo-650 Like Cadbury Gems? Understanding the Risks of Paracetamol Overuse
Dolo-650 has become a household name in India, especially since the Covid-19 pandemic. Whether it’s a mild headache, body ache, or slight fever, many people instinctively reach for this paracetamol-based tablet—often without consulting a doctor. A recent post by a US-based Indian doctor has sparked renewed discussion on this growing trend and the side effects of frequent paracetamol use.
The Viral Post That Sparked the Conversation
Earlier this week, Dr. Palaniappan Manickam, a gastroenterologist based in the US, took to social media to point out the casual attitude many Indians have toward Dolo-650. His post read, “Indians take Dolo 650 like it’s Cadbury Gems,” and quickly went viral.
- The post garnered over 25,000 likes, with users sharing anecdotes—like one saying their mother takes it twice a day for even the slightest discomfort.
- While many laughed, others raised serious concerns about the overuse of paracetamol and its potential health risks.
According to Dr. Vikram Jeet Singh, an internal medicine specialist, the post is not far from reality. While Dolo-650 is generally safe when used correctly, unmonitored self-medication can lead to harmful consequences.
What is Paracetamol or Dolo-650?
Dolo-650 is a widely used analgesic and antipyretic, primarily taken for pain relief and fever reduction.
- It became especially popular during the Covid-19 pandemic, with over 350 crore tablets sold during that period, according to Annals of Medicine and Surgery.
- The drug works by inhibiting prostaglandins, substances in the brain responsible for pain and fever.
Common Uses of Dolo-650
Dolo-650 is commonly used for:
- Fever management: Especially in viral fevers like Covid-19 and dengue.
- Pain relief: Effective for headaches, muscle pain, toothaches, and post-operative pain.
- Cold and flu: Often included in combination medications for managing common cold symptoms.
Dr. Singh notes that while effective, proper dosage and duration of use are critical to avoid complications.
Recommended Dosage Guidelines
The effectiveness of Dolo-650 largely depends on how and how much it is taken.
- Adults: Up to 650 mg every 4–6 hours, with a maximum of 4000 mg (6 tablets) in 24 hours.
- Children: Dosage depends on age and weight; pediatric formulations are available.
- The medicine should not be taken for more than 3 days for fever or 5 days for pain without medical advice.
5 Side Effects of Paracetamol (Dolo-650)
Overuse or overdose of paracetamol can cause serious health complications. Here are five key side effects to be aware of:
1. Liver Damage
Paracetamol is primarily processed by the liver.
- High doses can cause toxic buildup, leading to liver damage.
- This risk is amplified in people with pre-existing liver disease or those consuming alcohol regularly.
2. Nausea
Frequent or high doses may trigger nausea and stomach discomfort.
- Taking Dolo-650 on an empty stomach may worsen this symptom.
- A study in the British Journal of Clinical Pharmacology linked paracetamol use with episodes of nausea.
3. Low Blood Platelets (Thrombocytopenia)
Though rare, an overdose can result in decreased platelet count, affecting blood clotting.
- This may lead to easy bruising or bleeding.
- Immediate medical attention is advised if such symptoms appear.
4. Kidney Damage
Long-term use can stress the kidneys, particularly in those with existing kidney issues.
- Symptoms may include reduced urine output, fatigue, or swelling.
- Kidney damage is more likely when combined with dehydration or other medications.
5. High Blood Pressure
Regular consumption of high doses may elevate blood pressure levels.
- A BMJ study noted increased blood pressure in participants who took 4 grams of paracetamol daily.
- This risk is higher in individuals already managing hypertension.
Who Should Avoid or Be Cautious with Dolo-650?
While paracetamol is generally safe, certain groups should exercise caution or avoid it altogether:
- Liver disease patients: Even small doses can be harmful.
- Chronic alcohol consumers: Increased risk of liver toxicity.
- Allergy sufferers: Though rare, paracetamol allergies can trigger severe reactions.
- Kidney disease patients: High doses can worsen kidney function.
- Individuals on other paracetamol-containing drugs: Increases the risk of accidental overdose.
Final Thoughts: Use Dolo-650 Responsibly
Dolo-650 may offer quick relief, but it is not a one-size-fits-all solution.
- Know the right dosage, use it only when necessary, and consult a doctor if symptoms persist.
- Remember, over-the-counter does not mean risk-free.
- Treat it like medicine, not like Cadbury Gems.
By being informed and cautious, we can enjoy the benefits of paracetamol while protecting our liver, kidneys, and overall health.
